Vall d’Hebron Spine Research Unit (VHSRU) is a growing multidisciplinary group of professionals devoted to the study of complex spinal disorders. VHSRU is formed by 5 surgeons and 4 researchers organized in 4 different research lines: Pediatric and Adolescent Spinal Deformity, Adult Spinal Deformity, Spinal Cord Injuries in Trauma, Tumors and Degenerative Conditions and Cell therapy techniques in spinal surgery. VHSRU mission and main objective is to improve the treatment (mainly surgical), health care and, therefore, the quality of life of patients affected by spinal pathologies. During 2022, we have published 18 new manuscripts, been awarded with three new competitive research grants; two of them are funded by the Scoliosis Research Society (SRS) and one is funded by the Ministry of Science and Innovation of the Spanish Government (Carlos III Institute). We have been involved as coordinator or collaborator in 41 funded research projects (14 competitive and 27 noncompetitive).

Group Leader
Ferran Pellisé Uriquiza

Principal Investigator (PI)
Manuel Ramírez, Antonia Matamalas, Susana Nuñez

Ana García de Frutos, Sleiman Haddad

Nursing and Technical Staff
Maggie Barcheni, Marta Figueras, Clara Figueras, Laura Fruitós










D. C. Kieser, S. Yuksel, L. Boissiere, C. Yilgor, D. T. Cawley, K. Hayashi3, A. Alanay, F. S. Kleinstueck, F. Pellise, F. J. S. Perez‑Grueso, Vital Jean‑Marc, A. Bourghli, E. R. Acaroglu, I. Obeid, the European Spine Study Group
Impact of radiologic variables on item responses of ODI, SRS22 and SF‑36. in adult spinal deformity patients: diferential item functioning (DIF) analysis results from a multi‑center database
Eur Spine J. 2022 Jan 21.
DOI: doi: 10.1007/s00586-021-07088-5.
IF: 2.721

Pellisé F, Vila-Casademunt A, Núñez-Pereira S, Haddad S, Smith JS, Kelly MP, Alanay A, Shaffrey C, Pizones J, Yilgor Ç, Obeid I, Burton D, Kleinstück F, Fekete T, Bess S, Gupta M, Loibl M, Klineberg EO, Sánchez Pérez-Grueso FJ, Serra-Burriel M, Ames CP; European Spine Study Group, International Spine Study Group
Surgeons’ risk perception in ASD surgery: The value of objective risk assessment on decision making and patient counselling.
Eur Spine J. Mar 28. 2022
DOI: doi: 10.1007/s00586-022-07166-2
IF: 2.721

A F Mannion, A Elfering, T F Fekete, I J Harding, M Monticone, P Obid, T Niemeyer, U Liljenqvist, A Boss, L Zimmermann, A Vila-Casademunt, F J Sánchez Pérez-Grueso, J Pizones, F Pellisé, S Richner-Wunderlin, F S Kleinstück, I Obeid, L Boissiere, A Alanay, J Bagó
Shorter and sweeter: the 16-item version of the SRS questionnaire shows better structural validity than the 20-item version in young patients with spinal deformity
Spine Deform, 2022 Apr 27
DOI: doi: 10.1007/s00586-022-07166-2
IF: 1.091

Haddad S, Vila Casademunt A, Yilgor Ç, Nuñez Pereira S, Ramirez M, Pizones J, Alanay A, Kleinstuck F, Ibrahim Obeid I, Sánchez Pérez Grueso FJ, Pellisé F, European Spine Study Group
Combined anterior–posterior versus all‑posterior approaches for adult spinal deformity correction: a matched control study.
Eur Spine J, 2022 Jul;31(7):1754-1764.
DOI: doi: 10.1007/s00586-022-07249-0
IF: 2.721

Alejandro Gomez-Rice; Maria Capdevila-Bayo; Susana Nuñez-Pereira; Sleiman Haddad; Alba Vila-Casademunt; Francisco Javier Perez-Grueso; Frank Kleinstück; Ibrahim Obeid; Ahmet Alanay; Ferran Pellise; Javier Pizones; ESSG European Spine Study Group
A five-year follow-up of the effect of corrective surgery in young adults with idiopathic scoliosis
Spine Deformity, 31 December 2022
DOI: doi: 10.1007/s43390-023-00642-9
IF: 1.091

European Spine Study Group (ESSG): Multi-Center Prospective Study and Database: “Clinical Outcomes Following Conservative and Surgical Treatment of Adult Spine Deformity. Relevance of Coronal and Sagittal Spinopelvic Parameters”
Principal Investigator: Ferran Pellisé
Agency: Depuy Synthess Spine, Nuvasive and Medtronic
Funding: 5.992.260,58€
Period: 2010-now

Patología Vertebral en Pacientes con Síndrome de Marfan o de Loeys Dietz. Factores de Riesgo de Severidad y Progresión. Impacto en Calidad de Vida
Principal Investigator: Susana Nuñez
Agency: Ministerio de Ciencias y Innovación- Instituto de Carlos III
Funding: 26.195,18€
Period: 2022-2024

Spinal Pathology in Patients with Marfan or Loeys-Dietz Syndrome. Risk Factors for Severity and Progression
Principal Investigator: Susana Nuñez
Agency: SRS
Funding: 29700$
Period: 2022-2024

Self-perceived health status and healthcare consumption of Idiopathic Scoliosis patients treated more than 20 years ago
Principal Investigator: Ferran Pellisé
Agency: SRS
Funding: 450000$
Period: 2022-2024

A Multi-Center Post-Marketing Data collection Protocol to Evaluate the Performance of Orthofix Spine Devices
Principal Investigator: Ferran Pellisé
Agency: Orthofix
Funding: up to 837€ per patient
Period: 2021-now