The research activity of the group focuses on the study of pathologies such as asthma, COPD, pulmonary fibrosis, lung transplant, pulmonary hypertension, and sleep disorders. In this line, the Group is at present a partner of the EXIMIOUS project (H2020). In lung Transplant our goal is to perform personalize medicine to individualize treatment and monitor allograft function. In sleep disorders the goals of the program are to study sleep pathophysiology and study the effects that sleep and sleep disorders have on other organ systems. Regarding COPD, the group coordinate a multicenter project to know the effectiveness of palliative cures in the final phases of the disease. the group is part of the Catalonian Referral Unit for Cystic Fibrosis, which maintains the Spanish registry of bronchiectasis and patients with a1-antitrypsin deficit and has a line of research in rare diseases such as lymphangioleiomyomatosis, alpha-1-antitrypsin deficiency and hypersensitivity pneumonitis.

Group Leader
Mª Jesús Cruz Carmona, Jaume Ferrer Sancho

Principal Investigator (PI)
Miriam Barrechenguren Fernández, Cristina Berastegui Garcia, Susana Gómez Olles, Manuel López Meseguer, Marc Miravitlles Fernández, Victor Monforte Torres, Xavier Muñoz Gall, Iñigo Ojanguren Arranz, Eva Polverino, Berta Saez Gimenez,

Researchers
Antonio Álvarez Fernández, Irene Belmonte Mula, Carlos Bravo Masgoret, David Clofent Alarcón, Mario Culebras Amigo, María Luiza De Souza Galvao, Mª Ángeles Jiménez Fuentes, Mª José Jurado Luque, Karina Loor Reyes, Sergi Martí Beltran, Cèlia Milà Augé, Mercedes Pallero Castillo, Mª Antonia Ramón Belmonte, Esther Rodríguez González, Christian Romero Mesones, Odile Romero Santo-Tomas, Berta Sáez Gimenez, Gabriel Sampol Rubio, Julia Sampol Sirvent, Ana Villar Gómez

PhD Students
Meritxell Boada Pérez, David Espejo Castellanos, Almudena Felipe, Galo Granados Rosales, Marc Massa Gómez, David Soler Segovia, Alex Gabriela Nuñez Bubón, Eva Revilla Lopez, Victoria Ruiz de Miguel, Letizia Traversi

Lab Technicians
Victor Guerra Ruiz, Gerard Orriols, Sonia López Rodríguez, Rosa Lloria Verges, Montserrat Murillo Andrés, Jordi Rabadan Carnicero

Nursing and Technical Staff
Roser Escobar Fornieles, Georgina Farago

103

PUBLICATIONS

56.3%

%Q1

925

IMPACT FACTOR

8.98

AVERAGE IMPACT FACTOR

SELECTED ARTICLES

Sánchez-Díez S, Munoz X, Ojanguren I, Romero-Mesones C, Espejo D, Villar A, Gómez-Olles S, Cruz MJ.
YKL-40 and KL-6 Levels in Serum and Sputum of Patients Diagnosed With Hypersensitivity Pneumonitis
J Allergy Clin Immunol Pract. 2022 Sep;10(9):2414-2423.
DOI: doi: 10.1016/j.jaip.2022.06.031
IF: 11.022

Huang JT, Cant E, Keir HR, Barton AK, Kuzmanova E, Shuttleworth M, Pollock J, Finch S, Polverino E, Bottier M, Dicker AJ, Shoemark A, Chalmers JD
Endotyping COPD, Bronchiectasis and the ‘COPD-bronchiectasis Association
Am J Respir Crit Care Med. 2022 Aug 15;206(4):417-426
DOI: doi: 10.1164/rccm.202108-1943OC
IF: 30.53

Gottlieb J, Lepper PM, Berastegui C, Montull B, Wald A, Parmar J, Magnusson JM, Schonrath F, Laisaar T, Michel S, Larsson H, Vos R, Haneya A, Sandhaus T, Verschuuren E, le Pavec J, Tikkanen J, Hoetzenecker K
Lung transplantation for acute respiratory distress syndrome – a retrospective European Cohort Study
Eur Respir J. 2022 Jun 30;59(6)
DOI: doi: 10.1183/13993003.02078-2021
IF: 33.801

Cruz-Utrilla A, Perez-Olivares C, Martinez-Menaca A, Lopez-Meseguer M, Escribano-Subias P
Phenotypes of idiopathic pulmonary arterial hypertension.
Lancet Respir Med. 2022 Oct;10(10):e87
DOI: doi: 10.1016/S2213-2600(22)00290-9
IF: 102.64

Culebras M, Loor K, Sansano I, Persiva O, Clofent D, Polverino E, Felipe A, Osorio J, Munoz X, Alvarez A, Andreu J, Arjona M, Berastegui C, Barrecheguren M, Cardoso J, Cruz MJ, De Souza ML, Espejo D, Granados G, Jimenez MA, Lopez M, Ojanguren I, Pallero M, Ramon MA, Ramon Y Cajal S, Revilla EM, Romero C, Saez B, Sampol J, Velez E, Villar A
Histological Findings in Transbronchial Cryobiopsies Obtained From Patients After COVID-19
Chest. 2022 Mar;161(3):647-650.
DOI: doi: 10.1016/j.chest.2021.09.016.
IF: 11.39

Mapping Exposure-Induced Immune Effects: Connecting the Exposome and the Immunome (EXIMIOUS)
Principal Investigator: María Jesus Cruz, Xavier Muñoz Gall
Agency: European Commission (EXIMIOUS_H2020_SC1-BHC-2019)
Funding: 395,500 €
Period: 2020 - 2024

iABC: Inhaled antibiotics in bronchiectasis and cystic fibrosis
Principal Investigator: Eva Polverino
Agency: The Innovative Medicines Initiative (IABC_IMI2-2015)
Funding: 121,599 €
Period: 2017 - 2023

Characterisation and risk factors of PULmonary SEquelae in patients discharged after COVID-19 pneumonia (PULSE-COVID).
Principal Investigator: Xavier Muñoz Gall
Agency: Instituto de Salud Carlos III. Fis PI21/01046
Funding: 132,520 €
Period: 2022 - 2024

MicroRNA expression profiles in asthmatic patients with different disease phenotypes exposed to pollutants.
Principal Investigator: María Jesús Cruz Carmona
Agency: Instituto de Salud Carlos III. Fis PI21/01346
Funding: 141,570 €
Period: 2022 - 2024

Asthmatic exacerbations of viral origin and their impact on different asthmatic phenotypes: Etiology, immunological and inflammatory mechanisms.
Principal Investigator: Iñigo Ojanguren Arranz
Agency: Instituto de Salud Carlos III. Fis PI21/01100
Funding: 75,020 €
Period: 2022 - 2024